ATI Pathophysiology Practice Exam

Intermittent claudication is indeed a hallmark sign of peripheral artery disease (PAD). This condition occurs due to a narrowing or blockage of the arteries that supply blood to the limbs, most commonly the legs. As a result, when a person with PAD engages in physical activity, their muscles require more oxygen-rich blood, which the narrowed arteries cannot provide. This leads to cramping or pain in the legs, particularly during activities such as walking or climbing stairs. The pain typically resolves with rest, which is a distinctive characteristic of intermittent claudication.

The presence of this symptom is crucial for diagnosing PAD, as it reflects the reduced blood flow to the lower extremities, thereby indicating the severity and impact of the disease on mobility and overall circulation. Recognizing intermittent claudication can also be vital for enabling appropriate interventions to improve blood flow and reduce the risk of complications.