ATI Pathophysiology Practice Exam

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Which condition is primarily treated by medications that inhibit COX enzymes?

Hypertension.

Anemia.

Inflammation and pain.

The correct answer is focused on the treatment of inflammation and pain, which are conditions primarily managed by medications that inhibit COX (cyclooxygenase) enzymes. COX enzymes play a critical role in the conversion of arachidonic acid to prostaglandins, which are compounds that mediate inflammation, pain, and fever responses in the body.

Nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin and ibuprofen, act as COX inhibitors and are commonly used to alleviate conditions associated with inflammation, such as arthritis, muscle strains, and other painful conditions. These medications reduce the production of prostaglandins, thereby diminishing the inflammatory response and providing pain relief.

Other conditions mentioned do not directly involve treatment with COX inhibitors. For instance, hypertension is typically managed with antihypertensive medications rather than anti-inflammatory drugs. Anemia focuses on the deficiency of red blood cells and is addressed through supplements like iron or vitamin B12, rather than COX inhibition. Hyperthyroidism involves the management of thyroid hormone levels and is treated with antithyroid medications or radioiodine therapy, which is unrelated to COX activity.

Therefore, the treatment of inflammation and pain stands out as the primary application of medications that inhibit

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Hyperthyroidism.

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